It allows aqueous humour to be drained directly from the anterior chamber to Schlemm’s canal, bypassing the trabecular meshwork, which is believed to be the main site of outflow resistance. The first-generation iStent ® (Glaukos Corp, Laguna Hills, CA, USA) is the first minimally invasive glaucoma surgery device to be approved for the treatment of open-angle glaucoma. Their target is to lower intraocular pressure with minimal eye trauma and fewer complications.
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